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008 | 150903s2009 gw | o |||| 0|eng d | ||
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_a9783540887195 _99783540887195 |
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024 | 7 |
_a10.1007/9783540887195 _2doi |
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_a201509030938 _bVLOAD _c201405060305 _dVLOAD _y201402171200 _zstaff |
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_aMX-SnUAN _bspa _cMX-SnUAN _erda |
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050 | 4 | _aRC321-580 | |
100 | 1 |
_aGarcia-Verdugo, Jose Manuel. _eautor _9335612 |
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245 | 1 | 0 |
_aIdentification and Characterization of Neural Progenitor Cells in the Adult Mammalian Brain / _cby Jose Manuel Garcia-Verdugo, Arturo Alvarez-Buylla, Sara Gil-Perotín. |
264 | 1 |
_aBerlin, Heidelberg : _bSpringer Berlin Heidelberg, _c2009. |
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300 | _brecurso en línea. | ||
336 |
_atexto _btxt _2rdacontent |
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_acomputadora _bc _2rdamedia |
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_arecurso en línea _bcr _2rdacarrier |
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_aarchivo de texto _bPDF _2rda |
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490 | 0 |
_aAdvances in Anatomy, Embryology and Cell Biology, _x0301-5556 ; _v203 |
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500 | _aSpringer eBooks | ||
505 | 0 | _aHistoric Overview -- Research Methodologies for Adult Neurogenesis -- Neurogenesis in the Intact Adult Mammalian Central Nervous System -- Oncogenesis vs. Neurogenesis -- Adult Neurogenesis Under Pathological Stimulation: Ischemia -- Therapeutic Potential of Neural Stem Cells -- Concluding Remarks. | |
520 | _aThe concept of adult neurogenesis is relatively modern. It has surprised the scientific community and has ruled out the established idea that we are born with a set number of neurons. This discovery has come about progressively throughout the last century. In this work, the authors review some of the methods of research in adult neurogenesis placing emphasis on electron microscopy, a technique in which they are well practiced. Electron microscopy has been essential in the description of the cytoarchitecture of the different cell types populating the subventricular zone (SVZ), an area that underlies the lateral wall of the lateral ventricle, and where new neurons are generated during adulthood. Time-dependent studies have elucidated the temporal profile and lineage progression of SVZ cells from the generation of new cells to the integration into their target tissue, the olfactory bulb. Similarly, adult neurogenesis has been described in the dentate gyrus of the hippocampus, and is being investigated in other regions of the cerebrum and the spinal cord. Neurogenesis was first demonstrated in mice, but has been subsequently observed in other mammals such as rabbits, cows, monkeys, and humans. The meaning of neurogenesis in humans remains unknown, and it is essential to understand it for potential application in the therapy of neurological diseases. | ||
590 | _aPara consulta fuera de la UANL se requiere clave de acceso remoto. | ||
700 | 1 |
_aAlvarez-Buylla, Arturo. _eautor _9335613 |
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700 | 1 |
_aGil-Perotín, Sara. _eautor _9335614 |
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710 | 2 |
_aSpringerLink (Servicio en línea) _9299170 |
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776 | 0 | 8 |
_iEdición impresa: _z9783540887188 |
856 | 4 | 0 |
_uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/978-3-540-88719-5 _zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL) |
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