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008 150903s2009 gw | o |||| 0|eng d
020 _a9783540887195
_99783540887195
024 7 _a10.1007/9783540887195
_2doi
035 _avtls000352409
039 9 _a201509030938
_bVLOAD
_c201405060305
_dVLOAD
_y201402171200
_zstaff
040 _aMX-SnUAN
_bspa
_cMX-SnUAN
_erda
050 4 _aRC321-580
100 1 _aGarcia-Verdugo, Jose Manuel.
_eautor
_9335612
245 1 0 _aIdentification and Characterization of Neural Progenitor Cells in the Adult Mammalian Brain /
_cby Jose Manuel Garcia-Verdugo, Arturo Alvarez-Buylla, Sara Gil-Perotín.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg,
_c2009.
300 _brecurso en línea.
336 _atexto
_btxt
_2rdacontent
337 _acomputadora
_bc
_2rdamedia
338 _arecurso en línea
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
_2rda
490 0 _aAdvances in Anatomy, Embryology and Cell Biology,
_x0301-5556 ;
_v203
500 _aSpringer eBooks
505 0 _aHistoric Overview -- Research Methodologies for Adult Neurogenesis -- Neurogenesis in the Intact Adult Mammalian Central Nervous System -- Oncogenesis vs. Neurogenesis -- Adult Neurogenesis Under Pathological Stimulation: Ischemia -- Therapeutic Potential of Neural Stem Cells -- Concluding Remarks.
520 _aThe concept of adult neurogenesis is relatively modern. It has surprised the scientific community and has ruled out the established idea that we are born with a set number of neurons. This discovery has come about progressively throughout the last century. In this work, the authors review some of the methods of research in adult neurogenesis placing emphasis on electron microscopy, a technique in which they are well practiced. Electron microscopy has been essential in the description of the cytoarchitecture of the different cell types populating the subventricular zone (SVZ), an area that underlies the lateral wall of the lateral ventricle, and where new neurons are generated during adulthood. Time-dependent studies have elucidated the temporal profile and lineage progression of SVZ cells from the generation of new cells to the integration into their target tissue, the olfactory bulb. Similarly, adult neurogenesis has been described in the dentate gyrus of the hippocampus, and is being investigated in other regions of the cerebrum and the spinal cord. Neurogenesis was first demonstrated in mice, but has been subsequently observed in other mammals such as rabbits, cows, monkeys, and humans. The meaning of neurogenesis in humans remains unknown, and it is essential to understand it for potential application in the therapy of neurological diseases.
590 _aPara consulta fuera de la UANL se requiere clave de acceso remoto.
700 1 _aAlvarez-Buylla, Arturo.
_eautor
_9335613
700 1 _aGil-Perotín, Sara.
_eautor
_9335614
710 2 _aSpringerLink (Servicio en línea)
_9299170
776 0 8 _iEdición impresa:
_z9783540887188
856 4 0 _uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/978-3-540-88719-5
_zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
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999 _c298958
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