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001 301618
003 MX-SnUAN
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008 150903s2010 gw | o |||| 0|eng d
020 _a9783642137174
_99783642137174
024 7 _a10.1007/9783642137174
_2doi
035 _avtls000355220
039 9 _a201509030952
_bVLOAD
_c201405060347
_dVLOAD
_y201402191037
_zstaff
040 _aMX-SnUAN
_bspa
_cMX-SnUAN
_erda
050 4 _aRC321-580
100 1 _aSwerdlow, Neal R.
_eeditor.
_9339541
245 1 0 _aBehavioral Neurobiology of Schizophrenia and Its Treatment /
_cedited by Neal R. Swerdlow.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg :
_bImprint: Springer,
_c2010.
300 _axviii, 666 páginas
_brecurso en línea.
336 _atexto
_btxt
_2rdacontent
337 _acomputadora
_bc
_2rdamedia
338 _arecurso en línea
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
_2rda
490 0 _aCurrent Topics in Behavioral Neurosciences,
_x1866-3370 ;
_v4
500 _aSpringer eBooks
505 0 _aAssessing Function and Functional Outcome in Schizophrenia -- Antipsychotics and Metabolics in the Post-CATIE Era -- Pharmacological Strategies for Enhancing Cognition in Schizophrenia -- Treatment Implications of the Schizophrenia Prodrome -- Antipsychotic Drug Development -- Antipsychotic Dosing and Drug Delivery -- Functional Brain Imaging in Schizophrenia: Selected Results and Methods -- Neurochemical Imaging in Schizophrenia -- A Selective Review of Volumetric and Morphometric Imaging in Schizophrenia -- Neurophysiological Measures of Sensory Registration, Stimulus Discrimination, and Selection in Schizophrenia Patients -- Eye Tracking Dysfunction in Schizophrenia: Characterization and Pathophysiology -- Prepulse Inhibition of the Startle Reflex: A Window on the Brain in Schizophrenia -- Neurocognition in Schizophrenia -- Animal Models of Schizophrenia -- Models of Neurodevelopmental Abnormalities in Schizophrenia -- Prefrontal Cortical Circuits in Schizophrenia -- Thalamic Pathology in Schizophrenia -- Hippocampal Pathology in Schizophrenia -- Integrative Circuit Models and Their Implications for the Pathophysiologies and Treatments of the Schizophrenias -- Experimental Approaches for Identifying Schizophrenia Risk Genes -- Epigenetics of Schizophrenia -- Molecules, Signaling, and Schizophrenia.
520 _aSchizophrenia research is in a dynamic state; this text gives a foothold for where we stand today, and a map for where our field may move tomorrow. Chapters on treatment describe major changes in clinical and neural targets, and new technologies for drug delivery, even as we struggle to address adverse effects of old treatments. The text next reviews advances in the experimental analysis of the schizophrenias. Where we once faced a paucity of biological signals, our field now sees an expanding list of clear neural abnormalities, and chapters focus on those in circuitry connecting prefrontal cortex, thalamus and mesial temporal lobes. The rapid evolution of schizophrenia genetics is described: older strategies for finding disorder genes, jettisoned in favor of studies of aberrant copy number variants, rare mutations or DNA methylation, and of molecular signaling pathways that trigger downstream disturbances in critical brain circuits. With what we now know about the complex biology of the schizophrenias, a key question becomes whether we can manipulate this biology in a way that fundamentally changes the course of this disorder. This text provides a context for students, investigators and clinicians to understand this stage in our evolving field, and to look ahead to the future of schizophrenia research.
590 _aPara consulta fuera de la UANL se requiere clave de acceso remoto.
710 2 _aSpringerLink (Servicio en línea)
_9299170
776 0 8 _iEdición impresa:
_z9783642137167
856 4 0 _uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/978-3-642-13717-4
_zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
942 _c14
999 _c301618
_d301618