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008			150903s2011 gw | o |||| 0|eng d
020			_a9783642197031 _99783642197031
024	7		_a10.1007/9783642197031 _2doi
035			_avtls000356689
039		9	_a201509030539 _bVLOAD _c201405060408 _dVLOAD _y201402191259 _zstaff
040			_aMX-SnUAN _bspa _cMX-SnUAN _erda
050		4	_aRC321-580
100	1		_aHagan, Jim J. _eeditor. _9341084
245	1	0	_aMolecular and Functional Models in Neuropsychiatry / _cedited by Jim J. Hagan.
264		1	_aBerlin, Heidelberg : _bSpringer Berlin Heidelberg : _bImprint: Springer, _c2011.
300			_axiv, 394 páginas _brecurso en línea.
336			_atexto _btxt _2rdacontent
337			_acomputadora _bc _2rdamedia
338			_arecurso en línea _bcr _2rdacarrier
347			_aarchivo de texto _bPDF _2rda
490	0		_aCurrent Topics in Behavioral Neurosciences, _x1866-3370 ; _v7
500			_aSpringer eBooks
505	0		_aFrom the contents: Preface -- Mouse mutagenesis and disease models for Neuropsychiatric disorders. - Drosophila as a model organism for the study of neuropsychiatric disorders -- Transgenic animal models of Huntington’s Disease -- Molecular genetic models related to schizophrenia and psychotic illness: heuristics and challenges -- Animal Models of Depression: Molecular Perspectives.-Animal models of ADHD -- Mouse Models of Autism: Testing Hypotheses about Molecular Mechanisms -- Advances in animal models of drug addiction -- When the serotonin transporter gene meets adversity: The contribution of animal models to understanding epigenetic mechanisms in affective disorders and resilience -- Functional and Pharmacological MRI in understanding brain function at a systems level -- The pig as model animal for studying cognition and neurobehavioral disorders.
520			_aCommon neuropsychiatric diseases are associated with significant human and economic cost. The development of more effective treatments requires scientific progress on a broad front and animal models have a vital role to play in these advances, enabling exploration of the functional consequences of molecular changes at the cellular, systems and behavioural levels. This volume discusses some of the latest and most exciting advances in the field. The first five chapters consider developments in gene modification techniques, their applications in vivo across a variety of species and the latest work related to Schizophrenia, Huntington’s Disease and Major Depressive Disorder. Three chapters then focus on recent developments in Autism, Drug Dependence and Attention Deficit Hyperactivity Disorder. In the final four chapters consideration is given to the development of models in larger species and to emergent approaches, such as epigenetic regulation, gene X environment interactions and MRI as a tool for understanding the function of neuronal systems in non- human species, all of which are likely to play an increasingly important role in the scientific discourse related to neuropsychiatric diseases.
590			_aPara consulta fuera de la UANL se requiere clave de acceso remoto.
710	2		_aSpringerLink (Servicio en línea) _9299170
776	0	8	_iEdición impresa: _z9783642197024
856	4	0	_uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/978-3-642-19703-1 _zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
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999			_c302705 _d302705