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008 150903s2012 gw | o |||| 0|eng d
020 _a9783642227721
_99783642227721
024 7 _a10.1007/9783642227721
_2doi
035 _avtls000357530
039 9 _a201509030558
_bVLOAD
_c201405070217
_dVLOAD
_y201402191317
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040 _aMX-SnUAN
_bspa
_cMX-SnUAN
_erda
050 4 _aQP34-38
100 1 _aBrouns, Inge.
_eautor
_9343343
245 1 0 _aNovel Insights in the Neurochemistry and Function of Pulmonary Sensory Receptors /
_cby Inge Brouns, Isabel Pintelon, Jean-Pierre Timmermans, Dirk Adriaensen.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg,
_c2012.
300 _axii, 118 páginas 23 ilustraciones, 21 ilustraciones en color.
_brecurso en línea.
336 _atexto
_btxt
_2rdacontent
337 _acomputadora
_bc
_2rdamedia
338 _arecurso en línea
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
_2rda
490 0 _aAdvances in Anatomy, Embryology and Cell Biology,
_x0301-5556 ;
_v211
500 _aSpringer eBooks
520 _aAirway sensory nerve terminals are tailored to detect changes in the physical and chemical environment, thereby supplying local pulmonary information to the central nervous system. Since most intrapulmonary nerve terminals arise from fibres travelling in the vagal nerve, the classification of ‘sensory airway receptors’ is largely based on their action potential characteristics, electrophysiologically registered from the vagal nerve. However, the architecture of airways and lungs makes it nearly impossible to functionally locate the exact nerve terminals that are responsible for the transduction of a particular intrapulmonary stimulus. In this monograph we focus on three sensory receptor end organs in lungs that are currently morphologically well-characterised: smooth muscle-associated airway receptors (SMARs), neuroepithelial bodies (NEBs) and visceral pleura receptors (VPRs). Unravelling the main functional morphological and neurochemical characteristics of these sensory receptors using advanced immunohistochemistry and confocal microscopy has already allowed us to draw important conclusions about their potential function(s). The current development of ex vivo lung models for the selective identification of SMARs, NEBs and VPRs using vital staining will certainly facilitate direct physiological studies of these morphologically well-characterised airway receptors, since these models allow direct live studies of their functional properties.
590 _aPara consulta fuera de la UANL se requiere clave de acceso remoto.
700 1 _aPintelon, Isabel.
_eautor
_9343344
700 1 _aTimmermans, Jean-Pierre.
_eautor
_9343345
700 1 _aAdriaensen, Dirk.
_eautor
_9343346
710 2 _aSpringerLink (Servicio en línea)
_9299170
776 0 8 _iEdición impresa:
_z9783642227714
856 4 0 _uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/978-3-642-22772-1
_zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
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999 _c304498
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