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008			150903s2007 ja | o |||| 0|eng d
020			_a9784431384533 _99784431384533
024	7		_a10.1007/9784431384533 _2doi
035			_avtls000363759
039		9	_a201509030640 _bVLOAD _c201405070348 _dVLOAD _y201402211154 _zstaff
040			_aMX-SnUAN _bspa _cMX-SnUAN _erda
050		4	_aQP34-38
100	1		_aEbashi, Setsuro. _eeditor. _9349780
245	1	0	_aRegulatory Mechanisms of Striated Muscle Contraction / _cedited by Setsuro Ebashi, Iwao Ohtsuki.
264		1	_aTokyo : _bSpringer Japan, _c2007.
300			_axiii, 407 páginas _brecurso en línea.
336			_atexto _btxt _2rdacontent
337			_acomputadora _bc _2rdamedia
338			_arecurso en línea _bcr _2rdacarrier
347			_aarchivo de texto _bPDF _2rda
490	0		_aAdvances in Experimental Medicine and Biology, _x0065-2598 ; _v592
500			_aSpringer eBooks
505	0		_aHistorical Aspects -- Biological Actions of Calcium -- Professor Ebashi’s Journey Toward the Discovery of Troponin: A Personal Recollection -- Highlights of the History of Calcium Regulation of Striated Muscle -- Regulation by Troponin and Tropomyosin -- Troponin: Structure, Function and Dysfunction -- From the Crystal Structure of Troponin to the Mechanism of Calcium Regulation of Muscle Contraction -- Ca Ion and the Troponin Switch -- Disposition and Dynamics: Interdomain Orientations in Troponin -- Structural Basis for Calcium-Regulated Relaxation of Striated Muscles at Interaction Sites of Troponin with Actin and Tropomyosin -- Tropomyosin: Regulator of Actin Filaments -- Tropomyosin and Troponin Cooperativity on the Thin Filament -- Conformational Changes in Reconstituted Skeletal Muscle Thin Filaments Observed by Fluorescence Spectroscopy -- Calcium Structural Transition of Troponin in the Complexes, on the Thin Filament, and in Muscle Fibres, as Studied By Site-Directed Spin-Labelling EPR -- Crystal Structures of Tropomyosin: Flexible Coiled-Coil -- C. Elegans Model for Studying Tropomyosin and Troponin Regulations of Muscle Contraction and Animal Behavior -- Structural and Functional Analysis of Troponins from Scallop Striated and Human Cardiac Muscles -- Regulation in Cardiac Muscle and Disorders -- Cooperativity in the Regulation of Force and the Kinetics of Force Development in Heart and Skeletal Muscles -- Heart Failure, Ischemia/Reperfusion Injury and Cardiac Troponin -- Troponin Mutations in Cardiomyopathies -- Molecular Pathogenic Mechanisms of Cardiomyopathies Caused by Mutations in Cardiac Troponin T -- Cardiac Troponin Levels as a Preferable Biomarker of Myocardial Cell Degradation -- Regulation by Myosin -- Regulation by Myosin: How Calcium Regulates Some Myosins, Past and Present -- Calcium Inhibition of Physarum Myosin as Examined by the Recombinant Heavy Mero-Myosin -- Excitation-Contraction Coupling and Disorder -- Calcium-Induced Release of Calcium From the Sarcoplasmic Reticulum -- Dysregulation of the Gain of CICR Through Ryanodine Receptor1 (RyR1): The Putative Mechanism Underlying Malignant Hyperthermia -- Ion Pumping by Calcium ATPase of Sarcoplasmic Reticulum -- Regulation of Cell Functions by Ca2+ Oscillation -- Molecular Mechanisms of Muscle Contraction -- Evidence About the Structural Behaviour of Myosin Crossbridges During Muscle Contraction -- Structural Alterations of Thin Actin Filaments in Muscle Contraction by Synchrotron X-ray Fiber Diffraction -- Regulation of Muscle Contraction by Ca2+ and ADP: Focusing on the0 Auto-Oscillation (SPOC) -- Muscle Contraction Mechanism Based on Actin Filament Rotation -- On the Walking Mechanism of Linear Molecular Motors -- Modeling of the F-Actin Structure.
520			_aTroponin is a central subject in biochemical, biophysical, and physiological research. The discovery of this protein by Professor Setsuro Ebashi in 1965 initiated a new era in research into the molecular biology of the regulation of contraction in striated muscle. Troponin is one of the representative functional proteins in living organisms, and its structure and function have been studied extensively. Recently, the crystallographic structure of troponin ternary complex was determined successfully. Mutations in genes of cardiac isoforms of troponin have been shown to cause cardiomyopathies, and the pathogenic consequences of these genetic disorders are being investigated. In clinical medicine, troponin is now widely utilized as an excellent biochemical marker for myocardial infarction. This volume covers the entire spectrum of research on troponin and related muscle proteins, including pathophysiological and clinical aspects.
590			_aPara consulta fuera de la UANL se requiere clave de acceso remoto.
700	1		_aOhtsuki, Iwao. _eeditor. _9349781
710	2		_aSpringerLink (Servicio en línea) _9299170
776	0	8	_iEdición impresa: _z9784431384519
856	4	0	_uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/978-4-431-38453-3 _zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
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