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020 _a9783709115114
_99783709115114
024 7 _a10.1007/9783709115114
_2doi
035 _avtls000362653
039 9 _a201509030648
_bVLOAD
_c201405070333
_dVLOAD
_y201402211054
_zstaff
040 _aMX-SnUAN
_bspa
_cMX-SnUAN
_erda
050 4 _aRM1-950
100 1 _aGulbins, Erich.
_eeditor.
_9349977
245 1 0 _aSphingolipids in Disease /
_cedited by Erich Gulbins, Irina Petrache.
264 1 _aVienna :
_bSpringer Vienna :
_bImprint: Springer,
_c2013.
300 _aviii, 478 páginas 38 ilustraciones, 33 ilustraciones en color.
_brecurso en línea.
336 _atexto
_btxt
_2rdacontent
337 _acomputadora
_bc
_2rdamedia
338 _arecurso en línea
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
_2rda
490 0 _aHandbook of Experimental Pharmacology,
_x0171-2004 ;
_v216
500 _aSpringer eBooks
505 0 _aSphingolipids in Cancer: Sphingosine Kinase / Sphingosine 1-Phosphate Signaling in Cancer Therapeutics and Drug Resistance -- Using ASMase knockout Mice to Model Human Diseases -- New Perspectives on the Role of Sphingosine 1-Phosphate in Cancer -- Sphingolipids and Response to Chemotherapy -- Lung Cancer and Lung Injury: The Dual Role of Ceramide -- Sphingolipids Role in Radiotherapy for Prostate Cancer -- Sphingolipids in Cardio-Reno-vascular diseases: Sphingolipid Metabolism and Atherosclerosis -- Cardiovascular Effects of Sphingosine-1-Phosphate S1P -- Cross-Talk between Ceramide and Redox Signaling: Implications for Endothelial Dysfunction and Renal Disease -- Sphingolipids in Inflammation, Infection and Lung Diseases -- Sphingolipids in Lung Endothelial Biology and Regulation of Vascular Integrity -- Sphingolipids in Acute Lung Injury -- The Involvement of Sphingolipids in Chronic Obstructive Pulmonary Diseases -- Ceramide in Cystic Fibrosis.- Regulation of the Sphingosine Kinase/Sphingosine 1 Phosphate Pathway -- Bacterial Infections and Ceramide -- Viral Infections and Sphingolipids -- Ceramide in Plasma Membrane Repair -- Sphingolipids and Inflammatory Diseases of the Skin -- Sphingolipids in Diabetes -- Sphingolipids in Neuro-psychiatry and Muscle Diseases: Neuronal Forms of Gaucher Disease -- Sphingolipids in Neuroinflammation -- Sphingolipids in Psychiatric Disorders and Pain Syndromes -- Role of Sphingosine-1-Phosphate in Sceletal Muscle Cell Biology.
520 _aSphingolipids are lipid components of the plasma membrane of eukaryotic cells with an important function in signaling mechanisms in the cell. This  book provides insight into the physiological and pathophysiological role of sphingolipids and in particular its derivative ceramide. The function of Sphingolipids in cell signaling with regard to infectious and lung diseases, cancer, cardiovascular diseases and neuropsychiatric disorders are described and treated in distinct parts. Together with Volume 215 from the same Editors, the collection represents a unique, comprehensive work on Sphingolipids, providing information on both: Sphingolipid basic biology  as well as its important function in a (patho)physiological context. The book is written for scientists in pharmacology, biochemistry and cell biology with a focus on biomedical research as well as for clinicians in pharmacology, oncology, cardiology, neurology and infectious disease.   
590 _aPara consulta fuera de la UANL se requiere clave de acceso remoto.
700 1 _aPetrache, Irina.
_eeditor.
_9349978
710 2 _aSpringerLink (Servicio en línea)
_9299170
776 0 8 _iEdición impresa:
_z9783709115107
856 4 0 _uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/978-3-7091-1511-4
_zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
942 _c14
999 _c309607
_d309607