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020 _a9783764373788
_99783764373788
024 7 _a10.1007/3764373784
_2doi
035 _avtls000362715
039 9 _a201509030400
_bVLOAD
_c201404121552
_dVLOAD
_c201404091330
_dVLOAD
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040 _aMX-SnUAN
_bspa
_cMX-SnUAN
_erda
050 4 _aRC261-271
100 1 _aBignold, Leon P.
_eeditor.
_9350009
245 1 0 _aCancer: Cell Structures, Carcinogens and Genomic Instability /
_cedited by Leon P. Bignold.
264 1 _aBasel :
_bBirkhäuser Basel,
_c2006.
300 _axI, 375 páginas
_brecurso en línea.
336 _atexto
_btxt
_2rdacontent
337 _acomputadora
_bc
_2rdamedia
338 _arecurso en línea
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
_2rda
490 0 _aExperientia Supplementum ;
_v96
500 _aSpringer eBooks
505 0 _aCancer morphology, carcinogenesis and genetic instability: a background -- Abnormalities of chromatin in tumor cells -- Aneuploidy, stem cells and cancer -- The mode of action of organic carcinogens on cellular structures -- Metal ions and carcinogenesis -- Actions of ultraviolet light on cellular structures -- Actions of radiation on living cells in the “post-bystander” era -- Viral carcinogenesis and genomic instability -- Abnormalities of cell structures in tumors: apoptosis in tumors -- Molecular regulation of tumor angiogenesis: mechanisms and therapeutic implications -- Genetic and environmental factors in hereditary predisposition to tumors: a conceptual overview -- Effects of ionizing radiation on cellular structures, induced instability and carcinogenesis -- Genetic instability in human tumors -- Molecular mechanisms of human carcinogenesis -- Mechanisms of abnormal gene expression in tumor cells.
520 _aTumors can be induced by a variety of physical and chemical carcinogens. The resulting tumor cells are usually abnormal in their morphology and behavior and transmit their abnormalities to their daughter tumor cells. Most theories of the pathogenesis of tumors suggest that carcinogens in some way cause alterations either of the genomes or of inheritable patterns of gene expression in normal cells, which then cause morphological and behavioral changes. This volume presents a collection of articles aimed at the question by what genetic or epigenetic mechanisms carcinogens can cause morphological abnormalities of tumor cells. It includes reviews of cellular targets of known carcinogens, and presents varying viewpoints of how morphological abnormalities and the actions of carcinogens might be related. The volume will be of interest to all those who are involved in cancer research or in the prevention, diagnosis or management of tumors in humans or animals.
590 _aPara consulta fuera de la UANL se requiere clave de acceso remoto.
710 2 _aSpringerLink (Servicio en línea)
_9299170
776 0 8 _iEdición impresa:
_z9783764371562
856 4 0 _uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/3-7643-7378-4
_zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
942 _c14
999 _c309923
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