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020 _a9783764379759
_99783764379759
024 7 _a10.1007/9783764379759
_2doi
035 _avtls000362844
039 9 _a201509030649
_bVLOAD
_c201405070335
_dVLOAD
_y201402211059
_zstaff
040 _aMX-SnUAN
_bspa
_cMX-SnUAN
_erda
050 4 _aQR180-189.5
100 1 _aLey, Klaus.
_eeditor.
_9350616
245 1 0 _aAdhesion Molecules: Function and Inhibition /
_cedited by Klaus Ley.
264 1 _aBasel :
_bBirkhäuser Basel,
_c2007.
300 _axiv, 309 páginas 23 ilustraciones
_brecurso en línea.
336 _atexto
_btxt
_2rdacontent
337 _acomputadora
_bc
_2rdamedia
338 _arecurso en línea
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
_2rda
490 0 _aProgress in Inflammation Research
500 _aSpringer eBooks
505 0 _aCapture and rolling -- P-selectin glycoprotein ligand-1 (PSGL-1) -- L-selectin-mediated leukocyte adhesion and migration -- P- and E-selectin -- Firm adhesion -- Endothelial ICAM-1 functions in adhesion and signaling during leukocyte recruitment -- ?4-integrins: structure, function and secrets -- VCAM-1 and its functions in development and inflammatory diseases -- Lymphocyte function-associated antigen-1 (LFA-1) and macrophage antigen-1 (Mac-1): Cooperative partners in leukocyte emigration and function -- Transendothelial migration -- PECAM: Regulating the start of diapedesis -- Role of ?6?1 integrin in leukocyte adhesion and transmigration -- Vascular adhesion protein-1 (VAP-1) -- The role of endothelial cell-selective adhesion molecule (ESAM) in neutrophil emigration into inflamed tissues -- Structure and function of JAM proteins -- Promises and limitations of targeting adhesion molecules for therapy.
520 _aInflammatory cell recruitment requires the concerted action of at least five major sets of adhesion molecules: integrins, immunoglobulin-like molecules, selectins, carbohydrate structures serving as selectin ligands, and certain ectoenzymes. This volume gives a comprehensive overview on the most relevant leukocyte and endothelial adhesion molecules. The chapters are written by leaders in the field and focus on the biology, structure, function, and regulation of adhesion molecules. Currently approved adhesion molecule-based therapies are reviewed and an outlook for future approaches is also provided. The book is of interest to clinicians and scientists from immunology, physiology, cancer research, rheumatology, allergology, infectious diseases, gastroenterology, pulmonology and cardiology.
590 _aPara consulta fuera de la UANL se requiere clave de acceso remoto.
710 2 _aSpringerLink (Servicio en línea)
_9299170
776 0 8 _iEdición impresa:
_z9783764379742
856 4 0 _uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/978-3-7643-7975-9
_zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
942 _c14
999 _c310060
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