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001 | 310060 | ||
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005 | 20160429160339.0 | ||
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008 | 150903s2007 sz | o |||| 0|eng d | ||
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_a9783764379759 _99783764379759 |
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024 | 7 |
_a10.1007/9783764379759 _2doi |
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039 | 9 |
_a201509030649 _bVLOAD _c201405070335 _dVLOAD _y201402211059 _zstaff |
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_aMX-SnUAN _bspa _cMX-SnUAN _erda |
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050 | 4 | _aQR180-189.5 | |
100 | 1 |
_aLey, Klaus. _eeditor. _9350616 |
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245 | 1 | 0 |
_aAdhesion Molecules: Function and Inhibition / _cedited by Klaus Ley. |
264 | 1 |
_aBasel : _bBirkhäuser Basel, _c2007. |
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300 |
_axiv, 309 páginas 23 ilustraciones _brecurso en línea. |
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336 |
_atexto _btxt _2rdacontent |
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337 |
_acomputadora _bc _2rdamedia |
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338 |
_arecurso en línea _bcr _2rdacarrier |
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347 |
_aarchivo de texto _bPDF _2rda |
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490 | 0 | _aProgress in Inflammation Research | |
500 | _aSpringer eBooks | ||
505 | 0 | _aCapture and rolling -- P-selectin glycoprotein ligand-1 (PSGL-1) -- L-selectin-mediated leukocyte adhesion and migration -- P- and E-selectin -- Firm adhesion -- Endothelial ICAM-1 functions in adhesion and signaling during leukocyte recruitment -- ?4-integrins: structure, function and secrets -- VCAM-1 and its functions in development and inflammatory diseases -- Lymphocyte function-associated antigen-1 (LFA-1) and macrophage antigen-1 (Mac-1): Cooperative partners in leukocyte emigration and function -- Transendothelial migration -- PECAM: Regulating the start of diapedesis -- Role of ?6?1 integrin in leukocyte adhesion and transmigration -- Vascular adhesion protein-1 (VAP-1) -- The role of endothelial cell-selective adhesion molecule (ESAM) in neutrophil emigration into inflamed tissues -- Structure and function of JAM proteins -- Promises and limitations of targeting adhesion molecules for therapy. | |
520 | _aInflammatory cell recruitment requires the concerted action of at least five major sets of adhesion molecules: integrins, immunoglobulin-like molecules, selectins, carbohydrate structures serving as selectin ligands, and certain ectoenzymes. This volume gives a comprehensive overview on the most relevant leukocyte and endothelial adhesion molecules. The chapters are written by leaders in the field and focus on the biology, structure, function, and regulation of adhesion molecules. Currently approved adhesion molecule-based therapies are reviewed and an outlook for future approaches is also provided. The book is of interest to clinicians and scientists from immunology, physiology, cancer research, rheumatology, allergology, infectious diseases, gastroenterology, pulmonology and cardiology. | ||
590 | _aPara consulta fuera de la UANL se requiere clave de acceso remoto. | ||
710 | 2 |
_aSpringerLink (Servicio en línea) _9299170 |
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776 | 0 | 8 |
_iEdición impresa: _z9783764379742 |
856 | 4 | 0 |
_uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/978-3-7643-7975-9 _zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL) |
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_c310060 _d310060 |