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008 150903s2010 ne | o |||| 0|eng d
020 _a9789048190607
_99789048190607
024 7 _a10.1007/9789048190607
_2doi
035 _avtls000365672
039 9 _a201509030656
_bVLOAD
_c201405070417
_dVLOAD
_y201402211258
_zstaff
040 _aMX-SnUAN
_bspa
_cMX-SnUAN
_erda
050 4 _aR-RZ
100 1 _aLeung, Po Sing.
_eautor
_9310696
245 1 4 _aThe Renin-Angiotensin System: Current Research Progress in The Pancreas :
_bThe RAS in the Pancreas /
_cby Po Sing Leung.
264 1 _aDordrecht :
_bSpringer Netherlands :
_bImprint: Springer,
_c2010.
300 _axvI, 208 páginas
_brecurso en línea.
336 _atexto
_btxt
_2rdacontent
337 _acomputadora
_bc
_2rdamedia
338 _arecurso en línea
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
_2rda
490 0 _aAdvances in Experimental Medicine and Biology,
_x0065-2598 ;
_v690
500 _aSpringer eBooks
505 0 _aThe Pancreas -- Overview of the Pancreas -- Physiology of the Pancreas -- Common Pancreatic Disease -- The Renin-Angiotensin System (RAS) -- Circulating RAS -- Local RAS -- Pancreatic RAS -- Research Progress Of The Ras In Pancreas -- Basic Techniques for Pancreatic Research -- Current Research of the RAS in Diabetes Mellitus -- Current Research Concerning the RAS in Pancreatic Stem Cells -- Current Research of the RAS in Pancreatitis and Pancreatic Cancer.
520 _aThe human pancreas has vital roles in the regulation of glucose homeostasis and digestion and its dysfunction leads to pancreatic disease as diabetes and pancreatitis. Recent researches have highlighted the novel roles of a local renin-angiotensin system (RAS) in the pancreas and its clinical relevances; its inapprporiate activation leads to pancreatic endocrine and exocrine disease, notably type 2 diabetes. As such, manipulation of the overactive RAS may improve pancreatic islet cell function, cell mass and insulin sensitivity, as well as enhancing the growth and differentiation of pancreatic stem cells. Blockade of the RAS may be protective against pancreatitis and pancreatic cancer. The research outcome of current progress on the RAS in the pancreas should provide an alternative approach to preventing and treating, as well as curing pancreatic disease. This book discusses the progress of research on the renin-angiotensin system in the pancreas from the science to the bedside, providing a timely review of this expanding area. It consists of ten interrelated chapters covering subjects as: – Structure, physiology and disease of the pancreas – Biochemistry and physiology of the pancreatic renin-angiotensin system – RAS in diabetes, stem cells and pancreatitis This book is of special value to basic and clinical scientists, clinicians, graduate students, as well as novices in this field. ?
590 _aPara consulta fuera de la UANL se requiere clave de acceso remoto.
710 2 _aSpringerLink (Servicio en línea)
_9299170
776 0 8 _iEdición impresa:
_z9789048190591
856 4 0 _uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/978-90-481-9060-7
_zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
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