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020 _a9789400704954
_99789400704954
024 7 _a10.1007/9789400704954
_2doi
035 _avtls000366340
039 9 _a201509030701
_bVLOAD
_c201405070425
_dVLOAD
_y201402251333
_zstaff
040 _aMX-SnUAN
_bspa
_cMX-SnUAN
_erda
050 4 _aR-RZ
100 1 _aDas, Undurti N.
_eautor
_9355070
245 1 0 _aMolecular Basis of Health and Disease /
_cby Undurti N. Das.
264 1 _aDordrecht :
_bSpringer Netherlands :
_bImprint: Springer,
_c2011.
300 _axx, 583 páginas
_brecurso en línea.
336 _atexto
_btxt
_2rdacontent
337 _acomputadora
_bc
_2rdamedia
338 _arecurso en línea
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
_2rda
500 _aSpringer eBooks
505 0 _aAbout the Author -- Preface -- Dedication -- Chapter 1: Introduction -- Chapter 2: Health and Disease as two sides of the same coin -- Chapter 3: Inflammation -- Chapter 4: Essential fatty acids-Biochemistry, Physiology and Clinical Significance -- Chapter 5: Cell membrane organization -- Chapter 6: Low-grade systemic inflammation is common in iseases/disorders -- Chapter 7: Obesity -- Chapter 8: Hypertension -- Chapter 9: Insulin resistance, dyslipidemia, type 2 diabetes Mellitus and metabolic syndrome -- Chapter 10: Atherosclerosis -- Chapter 11: Osteoporosis -- Chapter 12: Alzheimer’s disease, schizophrenia and depression -- Chapter 13: Rheumatological conditions -- Chapter 14: Cancer -- Chapter 15: Aging -- Chapter 16: Adult diseases and low-grade systemic inflammation  have their origins in the perinatal period -- Chapter 17: Clinical implications.
520 _aThe book describes how the balance between pro- and anti-inflammatory molecules is related to health and disease. It is suggested that many diseases are initiated and their progress is influenced by inflammatory molecules and a decrease in the production and/or action of anti-inflammatory molecules and this imbalance between pro- and anti-inflammatory molecules seems to have been initiated in the perinatal period. This implies that strategies to prevent and manage various adult diseases should start in the perinatal period. An alteration in the metaolism of essential fatty acids and their anti-inflammatory molecules such as lipoxins, resolvins, protecitns, maresins and nitrolipids seems to play a major role in the pathobiology of several adult diseases. Based on these concepts, novel therapeutic approaches in the management of insulin resistance, obesity, type 2 diabetes mellitus, metabolic syndrome, cancer, lupus, rheumatoid arthritis and other auto-immune diseases are presented. Based on all these evidences, a unified concept that several adult diseases are due to an alteration in the balance between pro- and anti-inflammatory molecules is discussed and novel methods of their management are presented.
590 _aPara consulta fuera de la UANL se requiere clave de acceso remoto.
710 2 _aSpringerLink (Servicio en línea)
_9299170
776 0 8 _iEdición impresa:
_z9789400704947
856 4 0 _uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/978-94-007-0495-4
_zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
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999 _c313022
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