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008 | 150903s2011 ne | o |||| 0|eng d | ||
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_a9789400704954 _99789400704954 |
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024 | 7 |
_a10.1007/9789400704954 _2doi |
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_a201509030701 _bVLOAD _c201405070425 _dVLOAD _y201402251333 _zstaff |
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_aMX-SnUAN _bspa _cMX-SnUAN _erda |
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050 | 4 | _aR-RZ | |
100 | 1 |
_aDas, Undurti N. _eautor _9355070 |
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245 | 1 | 0 |
_aMolecular Basis of Health and Disease / _cby Undurti N. Das. |
264 | 1 |
_aDordrecht : _bSpringer Netherlands : _bImprint: Springer, _c2011. |
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300 |
_axx, 583 páginas _brecurso en línea. |
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336 |
_atexto _btxt _2rdacontent |
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337 |
_acomputadora _bc _2rdamedia |
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_arecurso en línea _bcr _2rdacarrier |
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_aarchivo de texto _bPDF _2rda |
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500 | _aSpringer eBooks | ||
505 | 0 | _aAbout the Author -- Preface -- Dedication -- Chapter 1: Introduction -- Chapter 2: Health and Disease as two sides of the same coin -- Chapter 3: Inflammation -- Chapter 4: Essential fatty acids-Biochemistry, Physiology and Clinical Significance -- Chapter 5: Cell membrane organization -- Chapter 6: Low-grade systemic inflammation is common in iseases/disorders -- Chapter 7: Obesity -- Chapter 8: Hypertension -- Chapter 9: Insulin resistance, dyslipidemia, type 2 diabetes Mellitus and metabolic syndrome -- Chapter 10: Atherosclerosis -- Chapter 11: Osteoporosis -- Chapter 12: Alzheimer’s disease, schizophrenia and depression -- Chapter 13: Rheumatological conditions -- Chapter 14: Cancer -- Chapter 15: Aging -- Chapter 16: Adult diseases and low-grade systemic inflammation have their origins in the perinatal period -- Chapter 17: Clinical implications. | |
520 | _aThe book describes how the balance between pro- and anti-inflammatory molecules is related to health and disease. It is suggested that many diseases are initiated and their progress is influenced by inflammatory molecules and a decrease in the production and/or action of anti-inflammatory molecules and this imbalance between pro- and anti-inflammatory molecules seems to have been initiated in the perinatal period. This implies that strategies to prevent and manage various adult diseases should start in the perinatal period. An alteration in the metaolism of essential fatty acids and their anti-inflammatory molecules such as lipoxins, resolvins, protecitns, maresins and nitrolipids seems to play a major role in the pathobiology of several adult diseases. Based on these concepts, novel therapeutic approaches in the management of insulin resistance, obesity, type 2 diabetes mellitus, metabolic syndrome, cancer, lupus, rheumatoid arthritis and other auto-immune diseases are presented. Based on all these evidences, a unified concept that several adult diseases are due to an alteration in the balance between pro- and anti-inflammatory molecules is discussed and novel methods of their management are presented. | ||
590 | _aPara consulta fuera de la UANL se requiere clave de acceso remoto. | ||
710 | 2 |
_aSpringerLink (Servicio en línea) _9299170 |
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_iEdición impresa: _z9789400704947 |
856 | 4 | 0 |
_uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/978-94-007-0495-4 _zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL) |
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