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020 _a9789048186228
_99789048186228
024 7 _a10.1007/9789048186228
_2doi
035 _avtls000365542
039 9 _a201509030655
_bVLOAD
_c201405070415
_dVLOAD
_y201402211255
_zstaff
040 _aMX-SnUAN
_bspa
_cMX-SnUAN
_erda
050 4 _aQH345
100 1 _aHarris, J. Robin.
_eeditor.
_9300276
245 1 0 _aCholesterol Binding and Cholesterol Transport Proteins: :
_bStructure and Function in Health and Disease /
_cedited by J. Robin Harris.
264 1 _aDordrecht :
_bSpringer Netherlands,
_c2010.
300 _axxI, 619 páginas
_brecurso en línea.
336 _atexto
_btxt
_2rdacontent
337 _acomputadora
_bc
_2rdamedia
338 _arecurso en línea
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
_2rda
490 0 _aSubcellular Biochemistry,
_x0306-0225 ;
_v51
500 _aSpringer eBooks
505 0 _aCholesterol–Protein Interaction: Methods and Cholesterol Reporter Molecules -- Cholesterol in Alzheimer’s Disease and other Amyloidogenic Disorders -- Cholesterol-Binding Viral Proteins in Virus Entry and Morphogenesis -- Sterol–Protein Interactions in Cholesterol and Bile Acid Synthesis -- Cholesterol Oxidase: Structure and Function -- Oxysterol-Binding Proteins -- High Density Lipoprotein Structure–Function and Role in Reverse Cholesterol Transport -- Lipoprotein Modification and Macrophage Uptake: Role of Pathologic Cholesterol Transport in Atherogenesis -- Cholesterol Interaction with Proteins That Partition into Membrane Domains: An Overview -- Caveolin, Sterol Carrier Protein-2, Membrane Cholesterol-Rich Microdomains and Intracellular Cholesterol Trafficking -- Cholesterol in Niemann–Pick Type C disease -- Protein Mediators of Sterol Transport Across Intestinal Brush Border Membrane -- Cholesterol at the Endoplasmic Reticulum: Roles of the Sigma-1 Receptor Chaperone and Implications thereof in Human Diseases -- Prominin-1: A Distinct Cholesterol-Binding Membrane Protein and the Organisation of the Apical Plasma Membrane of Epithelial Cells -- Mammalian StAR-Related Lipid Transfer (START) Domains with Specificity for Cholesterol: Structural Conservation and Mechanism of Reversible Binding -- Membrane Cholesterol in the Function and Organization of G-Protein Coupled Receptors -- Cholesterol Effects on Nicotinic Acetylcholine Receptor: Cellular Aspects -- Cholesterol and Myelin Biogenesis -- Cholesterol and Ion Channels -- The Cholesterol-Dependent Cytolysin Family of Gram-Positive Bacterial Toxins -- Cholesterol Specificity of Some Heptameric ?-Barrel Pore-Forming Bacterial Toxins: Structural and Functional Aspects -- Cholesterol-Binding Toxins and Anti-cholesterol Antibodies as Structural Probes for Cholesterol Localization.
520 _aKnowledge of cholesterol and its interaction with protein molecules is of fundamental importance in both animal and human biology. This book contains 22 chapters, dealing in depth with structural and functional aspects of the currently known and extremely diverse unrelated families of cholesterol-binding and cholesterol transport proteins. By drawing together this range of topics the Editor has attempted to correlate this broad field of study for the first time. Technical aspects are given considerable emphasis, particularly in relation cholesterol reporter molecules and to the isolation and study of membrane cholesterol- and sphingomyelin-rich "raft" domains. Cell biological, biochemical and clinical topics are included in this book, which serve to emphasize the acknowledged and important benefits to be gained from the study of cholesterol and cholesterol-binding proteins within the biomedical sciences and the involvement of cholesterol in several clinical disorders. It is hoped that by presenting this topic in this integrated manner that an appreciation of the fact that there is much more that needs to be taken into account, studied and understood than the widely discussed "bad and good cholesterol" associated, respectively, with the low- and high-density lipoproteins, LDL and HDL.
590 _aPara consulta fuera de la UANL se requiere clave de acceso remoto.
710 2 _aSpringerLink (Servicio en línea)
_9299170
776 0 8 _iEdición impresa:
_z9789048186211
856 4 0 _uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/978-90-481-8622-8
_zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
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999 _c313168
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