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008 | 150903s2010 ne | o |||| 0|eng d | ||
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_a9789048186228 _99789048186228 |
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024 | 7 |
_a10.1007/9789048186228 _2doi |
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_a201509030655 _bVLOAD _c201405070415 _dVLOAD _y201402211255 _zstaff |
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_aMX-SnUAN _bspa _cMX-SnUAN _erda |
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050 | 4 | _aQH345 | |
100 | 1 |
_aHarris, J. Robin. _eeditor. _9300276 |
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245 | 1 | 0 |
_aCholesterol Binding and Cholesterol Transport Proteins: : _bStructure and Function in Health and Disease / _cedited by J. Robin Harris. |
264 | 1 |
_aDordrecht : _bSpringer Netherlands, _c2010. |
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300 |
_axxI, 619 páginas _brecurso en línea. |
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336 |
_atexto _btxt _2rdacontent |
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337 |
_acomputadora _bc _2rdamedia |
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_arecurso en línea _bcr _2rdacarrier |
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_aarchivo de texto _bPDF _2rda |
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490 | 0 |
_aSubcellular Biochemistry, _x0306-0225 ; _v51 |
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500 | _aSpringer eBooks | ||
505 | 0 | _aCholesterol–Protein Interaction: Methods and Cholesterol Reporter Molecules -- Cholesterol in Alzheimer’s Disease and other Amyloidogenic Disorders -- Cholesterol-Binding Viral Proteins in Virus Entry and Morphogenesis -- Sterol–Protein Interactions in Cholesterol and Bile Acid Synthesis -- Cholesterol Oxidase: Structure and Function -- Oxysterol-Binding Proteins -- High Density Lipoprotein Structure–Function and Role in Reverse Cholesterol Transport -- Lipoprotein Modification and Macrophage Uptake: Role of Pathologic Cholesterol Transport in Atherogenesis -- Cholesterol Interaction with Proteins That Partition into Membrane Domains: An Overview -- Caveolin, Sterol Carrier Protein-2, Membrane Cholesterol-Rich Microdomains and Intracellular Cholesterol Trafficking -- Cholesterol in Niemann–Pick Type C disease -- Protein Mediators of Sterol Transport Across Intestinal Brush Border Membrane -- Cholesterol at the Endoplasmic Reticulum: Roles of the Sigma-1 Receptor Chaperone and Implications thereof in Human Diseases -- Prominin-1: A Distinct Cholesterol-Binding Membrane Protein and the Organisation of the Apical Plasma Membrane of Epithelial Cells -- Mammalian StAR-Related Lipid Transfer (START) Domains with Specificity for Cholesterol: Structural Conservation and Mechanism of Reversible Binding -- Membrane Cholesterol in the Function and Organization of G-Protein Coupled Receptors -- Cholesterol Effects on Nicotinic Acetylcholine Receptor: Cellular Aspects -- Cholesterol and Myelin Biogenesis -- Cholesterol and Ion Channels -- The Cholesterol-Dependent Cytolysin Family of Gram-Positive Bacterial Toxins -- Cholesterol Specificity of Some Heptameric ?-Barrel Pore-Forming Bacterial Toxins: Structural and Functional Aspects -- Cholesterol-Binding Toxins and Anti-cholesterol Antibodies as Structural Probes for Cholesterol Localization. | |
520 | _aKnowledge of cholesterol and its interaction with protein molecules is of fundamental importance in both animal and human biology. This book contains 22 chapters, dealing in depth with structural and functional aspects of the currently known and extremely diverse unrelated families of cholesterol-binding and cholesterol transport proteins. By drawing together this range of topics the Editor has attempted to correlate this broad field of study for the first time. Technical aspects are given considerable emphasis, particularly in relation cholesterol reporter molecules and to the isolation and study of membrane cholesterol- and sphingomyelin-rich "raft" domains. Cell biological, biochemical and clinical topics are included in this book, which serve to emphasize the acknowledged and important benefits to be gained from the study of cholesterol and cholesterol-binding proteins within the biomedical sciences and the involvement of cholesterol in several clinical disorders. It is hoped that by presenting this topic in this integrated manner that an appreciation of the fact that there is much more that needs to be taken into account, studied and understood than the widely discussed "bad and good cholesterol" associated, respectively, with the low- and high-density lipoproteins, LDL and HDL. | ||
590 | _aPara consulta fuera de la UANL se requiere clave de acceso remoto. | ||
710 | 2 |
_aSpringerLink (Servicio en línea) _9299170 |
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_iEdición impresa: _z9789048186211 |
856 | 4 | 0 |
_uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/978-90-481-8622-8 _zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL) |
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