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020 _a9789400755901
_99789400755901
024 7 _a10.1007/9789400755901
_2doi
035 _avtls000367610
039 9 _a201509030716
_bVLOAD
_c201405070444
_dVLOAD
_y201402251628
_zstaff
040 _aMX-SnUAN
_bspa
_cMX-SnUAN
_erda
050 4 _aRC261-271
100 1 _aSchmitz, Ulf.
_eeditor.
_9355459
245 1 0 _aMicroRNA Cancer Regulation :
_bAdvanced Concepts, Bioinformatics and Systems Biology Tools /
_cedited by Ulf Schmitz, Olaf Wolkenhauer, Julio Vera.
264 1 _aDordrecht :
_bSpringer Netherlands :
_bImprint: Springer,
_c2013.
300 _axii, 346 páginas 93 ilustraciones, 70 ilustraciones en color.
_brecurso en línea.
336 _atexto
_btxt
_2rdacontent
337 _acomputadora
_bc
_2rdamedia
338 _arecurso en línea
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
_2rda
490 0 _aAdvances in Experimental Medicine and Biology,
_x0065-2598 ;
_v774
500 _aSpringer eBooks
505 0 _aPreface -- 1 MicroRNAs in human cancer -- 2 Bioinformatics, non-coding RNAs and its possible application in personalized medicine -- 3 MicroRNA target prediction and validation -- 4 MicroRNA-regulated networks: the perfect storm for classical molecular biology, the ideal scenario for systems biology -- 5 The p53/microRNA network in cancer: experimental and bioinformatics approaches.-6 MicroRNAs in melanoma biology -- 7 MicroRNA in the lung -- 8 The E2F1-miRNA cancer progression network -- 9 Modeling of microRNA-transcription factor networks in cancer -- 10 Coordinated networks of microRNAs and transcription factors with evolutionary perspectives -- 11 Mathematical modeling of microRNA-mediated mechanisms of translation repression -- 12 Web resources for microRNA research -- 13 Discovery of microRNA regulatory networks by integrating multidimensional high-throughput data -- 14 Discovering the functional microRNA-mRNA regulatory modules in heterogeneous data -- 15 Elucidating the role of microRNAs in cancer through data mining techniques -- 16 Working together: Combinatorial regulation by microRNAs.  .
520 _aThis book reflects the current state of knowledge about the role of microRNAs in the formation and progression of solid tumours. The main focus lies on computational methods and their applications in combination with cutting edge experimental techniques that are used to approach all aspects of microRNA regulation in cancer. The use of high-throughput quantitative techniques makes an integrative experimental and computational approach necessary. This book will be a resource for researchers starting out with microRNA research, but is also intended for the experienced researcher who wants to incorporate concepts and tools from systems biology and bioinformatics into his work. Bioinformaticians and modellers are provided with a general perspective on microRNA biology, and the state-of-the-art in computational microRNA biology.
590 _aPara consulta fuera de la UANL se requiere clave de acceso remoto.
700 1 _aWolkenhauer, Olaf.
_eeditor.
_9315609
700 1 _aVera, Julio.
_eeditor.
_9355460
710 2 _aSpringerLink (Servicio en línea)
_9299170
776 0 8 _iEdición impresa:
_z9789400755895
856 4 0 _uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/978-94-007-5590-1
_zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
942 _c14
999 _c313296
_d313296