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020 _a9789400752917
_99789400752917
024 7 _a10.1007/9789400752917
_2doi
035 _avtls000367521
039 9 _a201509031049
_bVLOAD
_c201405070443
_dVLOAD
_y201402251625
_zstaff
040 _aMX-SnUAN
_bspa
_cMX-SnUAN
_erda
050 4 _aRC261-271
100 1 _aPalmieri, Diane.
_eeditor.
_9355922
245 1 0 _aCentral Nervous System Metastasis, the Biological Basis and Clinical Considerations /
_cedited by Diane Palmieri.
264 1 _aDordrecht :
_bSpringer Netherlands :
_bImprint: Springer,
_c2012.
300 _axI, 226 páginas 32 ilustraciones, 27 ilustraciones en color.
_brecurso en línea.
336 _atexto
_btxt
_2rdacontent
337 _acomputadora
_bc
_2rdamedia
338 _arecurso en línea
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
_2rda
490 0 _aCancer Metastasis - Biology and Treatment,
_x1568-2102 ;
_v18
500 _aSpringer eBooks
505 0 _aPreface -- List of Contributors -- 1 An Introduction to Brain Metastasis -- 2 The Molecular Biology of Brain Metastasis -- 3 The Brain Microenvironment -- 4 Vascular permeability within brain metastases -- 5 Imaging Experimental Brain Metastases -- 6 Possibilities of Targeted Therapies for Brain Metastasis -- 7  Surgery for Brain Metastasis -- 8  Is There A Role for Systemic Chemotherapy in the Treatment of Brain Metastases? -- 9  Radiation Therapy of CNS Metastases -- 10  Leptomeningeal Metastasis -- 11 Quality of Life in CNS Metastasis -- Index.
520 _aThis volume covers what is known regarding the natural history, basic biology, and clinical aspects, including imaging and treatment, of CNS metastasis. Three chapters cover the biology of the brain and brain metastases: molecular biology, includes what is known about specific genes/proteins involved in the process of metastasis and model systems to study brain metastasis; brain microenvironment, focuses on the resident cells of the microenvironment and their role in CNS metastasis; and the blood-brain barrier, includes a discussion of permeability with respect to brain metastases. A discussion of experimental imaging covers both the biology of brain metastasis from an imaging perspective and the use of imaging techniques to study brain metastases. The three clinical chapters discuss treatment options of surgery, chemotherapy, and radiation. The potential for novel targeted therapies is also addressed. Because of the uniqueness of the disease, leptomeningeal metastasis is discussed separately. The last chapter is devoted to quality of life issues associated with CNS metastasis.
590 _aPara consulta fuera de la UANL se requiere clave de acceso remoto.
710 2 _aSpringerLink (Servicio en línea)
_9299170
776 0 8 _iEdición impresa:
_z9789400752900
856 4 0 _uhttp://remoto.dgb.uanl.mx/login?url=http://dx.doi.org/10.1007/978-94-007-5291-7
_zConectar a Springer E-Books (Para consulta externa se requiere previa autentificación en Biblioteca Digital UANL)
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